Galectin-3 is a member of the galectin family, which are β-galactoside-binding lectins with ≥1 evolutionary conserved carbohydrate-recognition domain.1 Galectin-3 is expressed by various immune cells and is readily secreted by injured and inflammatory cells. Thus, galectin-3 is a novel candidate biomarker for the diagnosis, analysis, and prognosis of various cardiac diseases, including heart failure.2
Enzyme Immunoassay for the quantitative determination Galectin-3 in human serum and plasma.
RESOURCES
- Dong R, Zhang M, Hu Q, Zheng S, Soh A, Zheng Y, Yuan H. Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review). Int J Mol Med. 2018 Feb;41(2):599-614. doi: 10.3892/ijmm.2017.3311. Epub 2017 Dec 5. PMID: 29207027; PMCID: PMC5752178.
- Hara, A.; Niwa, M.; Kanayama, T.; Noguchi, K.; Niwa, A.; Matsuo, M.; Kuroda, T.; Hatano, Y.; Okada, H.; Tomita, H. Galectin-3: A Potential Prognostic and Diagnostic Marker for Heart Disease and Detection of Early Stage Pathology. Biomolecules 2020, 10, 1277. https://doi.org/10.3390/biom10091277
