Human Anti-Müllerian Hormone ELISA

Anti-Müllerian Hormone (AMH) is a glycoprotein belonging to the transforming growth factors (TGF-P). In females, AMH is secreted by granulosa cells of small follicles in the ovary.¹ Serum AMH levels strongly correlate with the number of growing follicles. Serum AMH levels are used in individualized follicle-stimulating hormone dosing protocols and may predict the risk of poor response or ovarian hyperstimulation syndrome.³ Serum concentrations of AMH gradually decrease and fall below detectable levels in menopause. AMH is the best current available measure of ovarian reserve for different clinical conditions.²

Enzyme Immunoassay for the quantitative determination of Anti-Müllerian Hormone (AMH) in human serum and plasma.

RESOURCES

1. Zec I, Tislaric-Medenjak D, Megla ZB, Kucak I. Anti-Müllerian hormone: a unique biochemical marker of gonadal development and fertility in humans. Biochem Med (Zagreb). 2011;21(3):219-30. doi: 10.11613/bm.2011.031. PMID: 22420235.
2. Broer SL, Broekmans FJ, Laven JS, Fauser BC. Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications. Hum Reprod Update. 2014 Sep-Oct;20(5):688-701. doi: 10.1093/humupd/dmu020. Epub 2014 May 12. PMID: 24821925.
3. Moolhuijsen LME, Visser JA. Anti-Müllerian Hormone and Ovarian Reserve: Update on Assessing Ovarian Function. J Clin Endocrinol Metab. 2020 Nov 1;105(11):3361–73. doi: 10.1210/clinem/dgaa513. PMID: 32770239; PMCID: PMC7486884.